Although proton therapy was used to treat patients in the middle of the 20th century, at first the method existed only in the framework of the experiment, in physical laboratories. The first clinical center for the treatment of cancer by protons was opened in 1990 in California, USA.

To date, according to the PTCOG data (Particle Therapy Co-Operative Group), 57 proton accelerators used for the treatment of diseases operate in the world, including facilities in scientific research institutes. Most of them work in the USA (19), Japan (12) and Germany (6). Another 37 centers with a period of commissioning in 2017-2021 are under construction. Most of the centers are being built in the United States (7), Great Britain (6) and China (6).

In Russia until recently there were only experimental devices in three physical research centers in Moscow, Moscow and Leningrad regions, specified in the PTCOG list.

The first in Russia and the CIS countries MIBS proton therapy center began to work in a test mode in September 2017 in St. Petersburg.

Active centers of proton therapy

Source: PTCOG data

COUNTRY Name BEAM DIRECTIONS START OF TREATMENT
Austria MedAustron 2 fixed beams, 1 gantry (under construction) 2017
Canada TRIUMF, Vancouver 1 fixed beam 1995
Czech Republic PTC Czech r.s.o., Prague 3 gantries, 1 fixed beam 2012
China WPTC, Wanjie, Zi-Bo 2 gantries, 1 fixed beam 2004
China SPHIC, Shanghai 3 fixed beams 2014
England Clatterbridge 1 fixed beam 1989
France CAL/IMPT, Nice 1 fixed beam, 1 gantry 1991, 2016
France CPO, Orsay 1 gantry, 2 fixed beams 1991, 2014
Germany HZB, Berlin 1 fixed beam 1998
Germany RPTC, Munich 4 gantries, 1 fixed beam 2009
Germany HIT, Heidelberg 2 fixed beams, 1 gantry 2009, 2012
Germany WPE, Essen 4 gantries, 1 fixed beam 2013
Germany UPTD, Dresden 1 gantry 2014
Germany MIT, Marburg 1 fixed beam 2015
Italy INFN-LNS, Catania 1 fixed beam 2002
Italy CNAO, Pavia 3 horiz., 1 vertical, fixed beams 2011
Italy APSS, Trento 2 gantries, 1 fixed beams 2014
Japan NCC, Kashiwa 2 gantries 1998
Japan HIBMC, Hyogo 1 gantry 2001
Japan PMRC 2, Tsukuba 2 gantries 2001
Japan Shizuoka Cancer Center 3 gantries, 1 fixed beam 2003
Japan STPTC, Koriyama-City 2 gantries, 1 fixed beam 2008
Japan MPTRC, Ibusuki 3 gantries 2011
Japan Fukui Prefectural Hospital PTC, Fukui City 2 gantries, 1 fixed beam 2011
Japan Nagoya PTC, Nagoya City, Aichi 2 gantries, 1 fixed beam 2013
Japan Hokkaido Univ. Hospital PBTC, Hokkaido 1 gantry 2014
Japan Aizawa Hospital PTC, Nagano 1 gantry 2014
Japan Tsuyama Chuo Hospital, Okayama 1 gantry 2016
Poland IFJ PAN, Krakow 1 fixed beam, 2 gantries 2011, 2016
Russia ITEP, Moscow 1 fixed beam 1969
Russia St.Petersburg 1 fixed beam 1975
Russia JINR 2, Dubna 1 fixed beam 1999
South Africa NRF - iThemba Labs 1 fixed beam 1993
South Korea KNCC, IIsan 2 gantrie, 1 fixed beam 2007
South Korea Samsung PTC, Seoul 2 gantries 2015
Sweden The Skandion Clinic,Uppsala 2 gantries 2015
Switzerland CPT, PSI, Villigen 2 gantries, 1 fixed beam 1984, 1996, 2013
Taiwan Chang Gung Memorial Hospital, Taipei 4 gantries, 1 fixed beam 2015
USA, CA. J. Slater PTC, Loma Linda 3 gantries, 1 fixed beam 1990
USA, CA. UCSF-CNL, San Francisco 1 fixed beam 1994
USA, MA. MGH Francis H. Burr PTC, Boston 2 gantries, 1 fixed beam 2001
USA, TX. MD Anderson Cancer Center, Houston 3 gantries, 1 fixed beam 2006
USA, FL. UFHPTI, Jacksonville 3 gantries, 1 fixed beam 2006
USA, OK. ProCure PTC, Oklahoma City 1 gantry, 3 fixed beams 2009
USA, PA. Roberts PTC,UPenn, Philadelphia 4 gantries, 1 fixed beam 2010
USA, IL. Chicago Proton Center, Warrenville 1 gantry, 3 fixed beams 2010
USA, VA. HUPTI, Hampton 4 gantries, 1 fixed beam 2010
USA, NJ. ProCure Proton Therapy Center, Somerset 4 gantries 2012
USA, WA. SCCA ProCure Proton Therapy Center, Seattle 4 gantries 2013
USA, MO. S. Lee Kling PTC, Barnes Jewish Hospital, St. Louis 1 gantry 2013
USA, TN. Provision Center for Proton Therapy, Knoxville 3 gantries 2014
USA, CA. Scripps Proton Therapy Center, San Diego 3 gantries, 2 fixed beams 2014
USA, LA. Willis Knighton Proton Therapy Cancer Center, Shreveport 1 gantry 2014
USA, FL. Ackerman Cancer Center, Jacksonville 1 gantry 2015
USA, MN. Mayo Clinic Proton Beam Therapy Center, Rochester 4 gantries 2015
USA, NJ. Laurie Proton Center of Robert Wood Johnson Univ. Hospital, New Brunswick 1 gantry 2015
USA, TX. Texas Center for Proton Therapy, Irving 2 gantries, 1 fixed beam 2015
USA, TN. St. Jude Red Frog Events Proton Therapy Center, Memphis 2 gantries, 1 fixed beam 2015
USA, AZ. Mayo Clinic Proton Therapy Center, Phoenix 4 gantries 2016
USA, MD. Maryland Proton Treatment Center, Baltimore 4 gantries, 1 fixed beam 2016
USA, FL. Orlando Health PTC, Orlando 1 gantry 2016
USA, OH. UH Sideman CC, Cleveland 1 gantry 2016